Hot water immersion acutely reduces peripheral glucose uptake in young healthy males: An exploratory crossover randomized controlled trial

Whether glucose concentration increases during heat exposure because of reduced peripheral tissue uptake or enhanced appearance is currently unknown. This study aimed to report concentrations in both capillary and venous blood response a challenge passive heating (PH) assess whether affects healthy males. Twelve male participants completed two experimental sessions, where they were asked undertake an oral tolerance test (OGTT) whilst immersed thermoneutral (CON, 35.9 (0.6) °C) hot water (HWI, 40.3 (0.5) for 120 min. Venous [glucose], rectal temperature, heart rate recorded. [Glucose] area under the curve HWI (907 (104) AU) differed from CON (719 (88) AU, all P < 0.001). No other differences noted (P > 0.05). Compared with CON, resulted greater temperature (37.1 (0.3) °C versus 38.6 (0.4) °C, respectively) (69 (12) bpm 108 (11) bpm, on cessation An OGTT results similar [glucose] immersion, whereas was when compared CON. indicates that acutely HWI.Abbreviations: AUC: Area curve; CON: Thermoneutral immersion trial; HWI: Hot OGTT: Oral test; PH: Passive heating; Tˉmsk: Mean skin temperature; Trec: Rectal